Associate Professor Email: zilong@ust.hk Laboratory Homepage (Best view with IE6 or above)

Representative Publications

1. Jin H., Sood R., Xu J., Zhen FH, English M.A., Liu P.P., and Wen Z.L. (2009). Definitive hematopoietic stem/progenitor cells manifest distinct differentiation output in the zebrafish VDA and PBI. Development. 136: 647-654.
    
2. Liu Y.M., Du L.S., Osato M., Teo E.H., Qian F., Jin H., Zhen F.H., Xu J., Guo L., Huang H.H., Chen J., Geisler R., Jiang Y.J., Peng J.R. and Wen Z.L. (2007). The zebrafish udu gene encodes a novel nuclear factor and is essential for primitive erythroid cell development. Blood, 110: 99-106..
    
3. Jin H., Xu J., and Wen, Z.L. (2007) Migratory path of definitive hematopoietic stem/progenitor cells during zebrafish development. Blood, 109: 5209-5214.
    
4. Qian F., Zhen F.H., Xu J., Huang M., Li W.Y., and Wen Z.L. (2007). Distinct functions for different scl isoforms in zebrafish primitive and definitive hematopoiesis. PLoS Biology, 5: 1110-1119.
    
5. Jin H., Xu J., Qian F., Du L.S., Tan C.Y., Lin Z.X., Peng J.R., and Wen Z.L. (2006). The 5’ zebrafish scl promoter targets transcription to the brain, spinal cord, hematopoietic and endothelial progenitors. Developmental Dynamics 235:60-67.
    
6. Qian F., Zhen F.H., Ong C.T., Jin S-W., Soo H. M., Stainier D.Y.R., Lin S., Peng J.R. and Wen Z.L. (2005). Microarray analysis of zebrafish cloche mutant using amplified cDNA and the identification of potential hematopoietic-endothelial target genes. Developmental Dynamics 233:1163-1172.
    
7. Chen J., Ruan H., Ng S.M., Gao C., Soo H.M., Wu W., Zhang Z.H., Wen Z.L., Lane D.P., and Peng J.R. (2005). Loss of function of def selectively up-regulates 113p53 expression to arrest expansion growth of digestive organs in zebrafish. Genes & Development 19:2900-2911.
    
8. Lo J., Lee S., Xu M., Liu F., Ruan H., Eun A., He Y., Wang W., Wen Z.L., and Peng J.R. (2003). 15,000 unique zebrafish EST clusters and their use in microarray for profiling gene expression patterns during embryogenesis. Genome Research 13:455-466.
    
9. Huang M., Qian F., Hu Y., Ang C, Li Z., and Wen Z.L. (2002). The chromatin-remodelling factor BRG1 selectively activates a subset of interferon α-inducible genes. Nature Cell Biology 4:774-781.

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