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LIFS 2210 Introduction to Biochemistry [3 Credit(s)]
[Previous Course Code(s): BICH 121] Major classes of biochemical
compounds; primary, secondary, tertiary and quaternary structures of
macromolecules; enzyme kinetics and mechanisms; biosynthesis of DNA
and RNA; transfer RNA and protein synthesis. Prerequisite(s): A
passing grade in AL/AS Biology OR in AL/AS Chemistry
Reference(s):
- Mathews and Van Holde, Biochemistry
LIFS 2720 Introductory Biochemical Laboratory [2 Credit(s)]
[Previous Course Code(s): BICH 172] Investigation of the properties
of enzymes, lipids, carbohydrates and nucleic acids by
physicochemical methods and specific assays; purification and
quantitation of biochemical compounds by various biochemical
techniques.
LIFS 2820 Biochemical Laboratory Techniques [1 Credit(s)]
[Previous Course Code(s): BICH 182] Principles of biochemical
techniques including spectrophotometry, column chromatography,
electrophoresis, metabolite assay, enzyme assay, nucleic acid
isolation and protein isolation.
LIFS 3006 Research in Modern Biochemistry [2 Credit(s)]
[Previous Course Code(s): BICH 200B] The course is a teaching
laboratory course comprising a coherent set of experiments based on
a small scale project on selected research topic. Various topics of
research project will be offered according to the expertise of three
core research groups in the department, namely, Structural Biology,
Cellular Regulation, and Biotechnology & Medicinal Biochemistry. The
course bears 2 credits and consists of 6 hours of laboratory work
per week, which is supplemented with pre-laboratory talks and
lectures in-between experiments. It will be taught by Life Science
faculty members, with a demonstrator and/or research technician
supervising all experiments. Approval of the course instructor is
needed for students to enroll in this course. Graded P or F.
Prerequisite(s): LIFS 2210, LIFS 2220, LIFS 2720 and LIFS 2820
LIFS 3010 Molecular and Cellular Biochemistry I [3 Credit(s)]
[Previous Course Code(s): BICH 201] Replication and roles of nucleic
acids in cellular and viral systems; genome organization,
vector-host systems, expression and regulation of genes; catalytic
RNA, genetic code evolution, RNA modification and processing, and
anti-sense systems. Prerequisite(s): LIFS 2210 and LIFS 2220
Corequisite(s): LIFS 3110 and LIFS 3210
Reference(s):
- Mathews and Van Holde, Biochemistry
- Lewin, Genes V
LIFS 3110 Biotechnological Application of Recombinant DNA
Techniques [2 Credit(s)]
[Previous Course Code(s): BICH 211] Basic recombinant DNA technique,
DNA transfection, DNA construction. DNA sequencing, PCR,
bioinformatic analysis, identification of genes by hybridization.
Exclusion(s): LIFS 3120 Prerequisite(s): LIFS 2210 and LIFS 2220
Corequisite(s): LIFS 3010 and LIFS 3210
LIFS 3210 Principles of Recombinant DNA Technology [1 Credit(s)]
[Previous Course Code(s): BICH 221] Lecture component of
Biochemistry of Nucleic Acids. Plasmid isolation, gene cloning,
restriction mapping; DNA sequencing, and identification of genes and
gene products by blotting procedures. Exclusion(s): LIFS 3120
Prerequisite(s): LIFS 2210 and LIFS 2220 Corequisite(s): LIFS 3010
and LIFS 3110
LIFS 4550 Biochemistry of Nutrition [3 Credit(s)]
[Previous Course Code(s): BISC 355] The biochemistry of major food
ingredients including proteins, oil, carbohydrates, vitamins and
minerals; functional and nutritional properties will be emphasized.
Prerequisite(s): LIFS 2210
LIFS 4630 Advanced Topics in Biotechnology [3 Credit(s)]
[Previous Course Code(s): BISC 363] Principles and roles of various
disciplines in biotechnology, including manipulation of various cell
types, gene expression, immunochemistry, protein engineering,
downstream processing, cell and enzyme immobilization, and
fermentation; case studies in the development and applications of
biotechnology. Prerequisite(s): LIFS 3110 or LIFS 3120
LIFS 4760 Biochemistry of Diseases [3 Credit(s)]
[Previous Course Code(s): BISC 376] This course covers the clinical
manifestations, physiology, pathophysiology and treatment of common
human diseases, with focus on the underlying biochemical basis of
the diseases and treatment. Prerequisite(s): LIFS 2210
LIFS 4971 Biochemical Research I [3 Credit(s)]
[Previous Course Code(s): BICH 397] A research project conducted
under faculty supervision: design of experiments, analysis of data,
submission of a written report. Approval of the course instructor is
needed for students to enroll in this course. Prerequisite(s): LIFS
3010 and LIFS 3110
LIFS 1901 General Biology I [3 Credit(s)]
This course targets science students not having taken HKDSE 1x
Biology or AL/AS Biology. It provides students with a general
overview of fundamental biology: basic characteristics of life (the
chemistry of life, cells), vital life processes (respiration,
photosynthesis, genetics), essential concepts of evolution and
ecology, and so on. Exclusion(s): Level 3 or above in HKDSE 1x
Biology, a passing grade in AL/AS Biology
LIFS 1902 General Biology II [3 Credit(s)]
This course targets science students who have knowledge about
fundamental biology (including the chemistry of life, cells,
respiration, photosynthesis, genetics, evolution, and basic ecology)
through HKDSE 1x Biology, AL/AS Biology or LIFS 1901. More advanced
topics of general biology will be discussed in this course,
including diversity of life, plant and animal biology, applied
ecology, and so on. Prerequisite(s): LIFS 1901 OR level 3 or above
in HKDSE 1x Biology OR a passing grade in AL/AS Biology
LIFS 1904 Laboratory for General Biology II [1 Credit(s)]
This is a practical course accompanied by the lecture course LIFS
1902. It provides students with some basic concepts and hands-on
experience in biological investigation within the areas covered by
LIFS1902, including plant biology, human biology and ecology. The
emphasis is on the understanding and application of the scientific
principles underlying the experiments. Graded P or F. Prerequisite(s):
LIFS 1901 OR level 3 or above in HKDSE 1x Biology OR a passing grade
in AL/AS Biology Corequisite(s): LIFS 1902
LIFS 2030 Nature of Biochemistry and Biotechnology [3 Credit(s)]
[Previous Course Code(s): BISC 103] Major classes of biochemical
compounds; enzymic catalysis, metabolic pathways; genetic
information; genetic coding of protein synthesis, genetic
engineering; industrial, medical and agricultural applications of
biochemistry. Exclusion(s): LIFS 2210, LIFS 2220 Prerequisite(s): A
passing grade in AL Biology
Reference(s):
- Boyer, Concepts in Biochemistry
LIFS 2220 Intermediary Metabolism [3 Credit(s)]
[Previous Course Code(s): BICH 122] Principles of bioenergetics and
cellular structures; glycolysis, citric acid cycle, electron
transport, oxidative phosphorylation and chemiosmosis; carbohydrate,
lipid, amino acid and nucleotide metabolism; photosynthesis and
nitrogen fixation. Prerequisite(s): LIFS 2210
Reference(s):
- Mathews and Van Holde, Biochemistry
LIFS 2720 Introductory Biochemical Laboratory [2 Credit(s)]
[Previous Course Code(s): BICH 172] Investigation of the properties
of enzymes, lipids, carbohydrates and nucleic acids by
physicochemical methods and specific assays; purification and
quantitation of biochemical compounds by various biochemical
techniques.
LIFS 2820 Biochemical Laboratory Techniques [1 Credit(s)]
[Previous Course Code(s): BICH 182] Principles of biochemical
techniques including spectrophotometry, column chromatography,
electrophoresis, metabolite assay, enzyme assay, nucleic acid
isolation and protein isolation.
LIFS 3005 Research in Modern Biochemistry [2 Credit(s)]
[Previous Course Code(s): BICH 200A] The course is a teaching
laboratory course comprising a coherent set of experiments based on
a small scale project on selected research topic. Various topics of
research project will be offered according to the expertise of three
core research groups in the department, namely, Structural Biology,
Cellular Regulation, and Biotechnology & Medicinal Biochemistry. The
course bears 2 credits and consists of 6 hours of laboratory work
per week, which is supplemented with pre-laboratory talks and
lectures in-between experiments. It will be taught by Life Science
faculty members, with a demonstrator and/or research technician
supervising all experiments. Approval of the course instructor is
needed for students to enroll in this course. Graded P or F.
Prerequisite(s): LIFS 2210, LIFS 2220, LIFS 2720 and LIFS 2820
LIFS 3020 Molecular and Cellular Biochemistry II [3 Credit(s)]
[Previous Course Code(s): BICH 202] Cell structure; the molecular
biology of cell signaling and cell cycle control; oncogenes and
tumor suppressor genes; the mechanism of cell division; cell
junctions and adhesion; cytoskeleton; programmed cell death.
Prerequisite(s): LIFS 3010
LIFS 3070 Biophysics and Physical Biochemistry [3 Credit(s)]
[Previous Course Code(s): BISC 207] An introduction to the
principles and applications of biophysical techniques, including
ultra-centrifugation, electrophoresis, optical and NMR
spectroscopies, scattering and diffraction techniques, and
radioisotope labeling and detection techniques. Basic concepts of
thermodynamics at the cellular level and chemical kinetics.
Prerequisite(s): LIFS 2210
LIFS 4190 Advanced Cell Biology [3 Credit(s)]
[Previous Course Code(s): BISC 319] Recent advances in the study of
cellular structure and function; molecular mechanisms of cell
function; cell division and cell cycle; cell-cell signaling;
molecular and cellular control in small eukaryotes; control of cell
differentiation and morphogenesis. Prerequisite(s): LIFS 3020 or
LIFS 3030
LIFS 4380 Pharmacology and Toxicology [3 Credit(s)]
[Previous Course Code(s): BISC 338] Fundamental concepts of drug
action and toxicity; clinically useful agents in central and
peripheral disorders; toxicology of drugs and agents that are
hazardous to living organisms. Prerequisite(s): LIFS 3040 or LIFS
3060
LIFS 4540 Structure and Function of Proteins [3 Credit(s)]
[Previous Course Code(s): BISC 354] Determination of protein
sequences and three-dimensional structures; relationship between
structure and function; principles of protein design and
engineering; molecular, biochemical and genetic approaches to study
protein function and regulation. Prerequisite(s): LIFS 2210
Reference(s):
- Creighton, Proteins, Structures and Molecular Properties
LIFS 4580 Bioinformatics [3 Credit(s)]
[Previous Course Code(s): BISC 358] Frontier knowledge in
bioinformatics. From the fundamental data mining, to the advanced
topics in evolutionary analysis, protein structure prediction and
genomics study. Both basic and applied aspects of bioinformatics
will be explored in this course. Prerequisite(s): LIFS 2210
LIFS 4620 Advanced Biological Chemistry [3 Credit(s)]
[Previous Course Code(s): BISC 362] Advanced studies of biological
macromolecules; functional genomics and proteomics; laboratory
techniques in modern biochemistry; milestone discoveries in
biochemistry. Prerequisite(s): LIFS 2210
LIFS 4660 Biotechnology Seminar [4 Credit(s)]
[Previous Course Code(s): BICH 366] An in-depth reading and analysis
by the student of selected facets of biotechnology leading to the
submission of a written report, and its presentation in a seminar.
Approval of the course instructor is needed for students to enroll
in this course.
LIFS 4950 Neurochemistry [3 Credit(s)]
[Previous Course Code(s): BISC 395] Introduction to the molecular
understanding of brain function, building upon the basis of
biochemistry and biology. Four specific themes are covered: (i)
structural neurochemistry and neural membranes; (ii) synapses,
transmitters and receptors; (iii) cellular and (iv) medical and
behavioral neurochemistry. Prerequisite(s): LIFS 2210
LIFS 4981 Biochemical Research II [4 Credit(s)]
[Previous Course Code(s): BICH 398] A research project conducted
under faculty supervision: design of experiments, analysis of data,
submission of a written report and presentation of a seminar.
Approval of the course instructor is needed for students to enroll
in this course. Prerequisite(s): LIFS 4971
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BSc in Biochemistry Programme