Prof. Yusong Guo and his collaborators, Prof. Liwen Jiang at the Chinese University of Hong Kong and Prof. Yan Yan at LIFS of HKUST, have discovered a novel molecular mechanism that controls the delivery of a key protein in PCP. Their findings, published in the Journal of Biological Chemistry, can provide useful guidance on the development of new drugs for cancer treatment.
A research team led by Prof. Tuan Anh NGUYEN, Assistant Professor in the Division of Life Science at HKUST, recently discovered how RNA elements in the upper stem of pri-mRNAs affect the action of Microprocessor.
The National Natural Science Foundation of China (NSFC) just announced the award list of the 2019 Excellent Young Scientists [NSFC-EYS优青(港澳)]. We are delighted to share with you that our faculty Prof. Jiguang Wang (LIFS/CBE) is among the awardees.
Prof. Mingjie Zhang published in Cell Reports that a point mutation of Myo7a (Myosin VIIa) found in Usher syndrome patients leads to disruption of the hair cell tip-link protein complex formation through liquid-liquid phase separation.
Prof. Mingjie Zhang and his collaborators decoded the binding mechanisms governing the WW domain tandem-containing proteins. Their findings, published in eLife, reveal the recognition mechanisms of tandem WW domains with their peptide ligands which can serve as a guiding tool for functional studies of WW domain-containing proteins in the future.
Prof. Mingjie Zhang and his team reported that stargazin uses its entire C-terminal tail bind PSD-95 via a specific and multivalent interaction mode. Their findings, published in Neuron, reveal the mechanism of AMPA receptor synaptic trafficking and transmission at the neuronal synapses.