An introduction to bioinformatic analysis in life sciecne. Students will learn about the principles and approaches used in working with genetic, genomic and proteomic data. Applications to basic science and translational research will also be introduced. No experience in computer programing is required.
IMPORTANT NOTE: Last offering term of this course – Fall 2020-2021.
[Alternative code: BIEN 3020] Biological physics involves the application of physics to achieve an understanding of life processes. This is the second of a two-course series that will prepare advanced undergraduates for research and technical work in Biological physics. It covers advanced biological physics such as molecular and cellular biological physics, photophysics, single-molecule biophysics, medical biophysics, membrane biological physics, neurobiophysics, biostatistics, biomathematics, bioinformatics, computational biology and protein engineering. At the conclusion of this course, students will be able to critically assess primary research literature written for a general scientific audience. They will also be prepared for mentored practical research investigations or professional job related to biological physics.
Credit(s): 3
Prerequisite(s):
BIPH 2010 AND (LIFS 2010 OR LIFS 2040) AND (PHYS 1114 OR PHYS 1314)
Chromosome biology and epigenetics is an important field highly relevant to human health. This course will cover recent advances in the fields of epigenetics and chromosome biology.
The biochemistry of major food ingredients including proteins, oil, carbohydrates, vitamins and minerals; functional and nutritional properties will be emphasized.
Determination of protein sequences and three-dimensional structures; relationship between structure and function; principles of protein design and engineering; molecular, biochemical and genetic approaches to study protein function and regulation.
[LIFS 4380 is offered in every other year.]
Fundamental concepts of drug action and toxicity; clinically useful agents in central and peripheral disorders; toxicology of drugs and agents that are hazardous to living organisms.
IMPORTANT NOTE: This course will not be offered in Spring 2021
Overview of aquaculture in relation to food production and biotechnology, including problems and prospects. Examples of aquacultured aquatic species and aquaculture biotechnology enterprises. Aquaculture biology and practices: larval rearing, nutritional practices and feeds, reproductive control, application of genetics and genetic manipulations.
[LIFS 4190 is offered in every other year.]
Recent advances in the study of cellular structure and function; molecular mechanisms of cell function; cell division and cell cycle; cell-cell signaling; molecular and cellular control in small eukaryotes; control of cell differentiation and morphogenesis.
Fundamentals in the epidemiology, etiology and treatment of cancers; basic mechanisms of carcinogenesis. For LIFS and BIBU students in their third year (for 3Y degree) or fourth year (for 4Y degree) of study.
Cellular, biochemical and genetic basis of immunity; cells in immune response, antigens and antigen recognition; antibodies and the generation of diversity; major histocompatibility complex; cell mediated immune response; regulation of immune response; autoimmunity, tissue transplantation and rejection.
